Quantitative analysis of a parasitic antiviral strategy.
نویسندگان
چکیده
We extended a computer simulation of viral intracellular growth to study a parasitic antiviral strategy that diverts the viral replicase toward parasite growth. This strategy inhibited virus growth over a wide range of conditions, while minimizing host cell perturbations. Such parasitic strategies may inhibit the development of drug-resistant virus strains.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 48 3 شماره
صفحات -
تاریخ انتشار 2004